Symptoms of Hodgkin Lymphoma
by Debra Wood, RN
Hodgkin lymphoma symptoms will appear as the disease progresses. If you experience any of these symptoms, do not assume it is due to cancer. Many of these symptoms can be caused by other, less serious conditions, like an infection. However, it is still important to discuss them with your doctor. Early detection and treatment improve outcomes for both cancer and other health conditions.
Swollen Lymph Nodes
The most common symptom is painless swelling of the lymph nodes. Lymph nodes in the neck, collarbone, armpit, or groin are most affected, but swelling can occur in lymph nodes anywhere in the body. Swollen lymph nodes can be felt just under the skin and may change in size over the course of time. If the lymph nodes shrink, it does not mean the problem is gone. In general, if you have swelling that lasts longer than 2 weeks, it should be reported to your doctor.
Though rare, some people experience pain in the affected lymph nodes after consuming alcohol. Pain onset may occur immediately after drinking or several hours later. It is not known what causes this phenomenon.
Symptoms vary based on the area affected by swollen lymph nodes. Swelling may press on nearby blood vessels, nerves, or other structures. This compression may interfere with normal function or cause pain. Symptoms by locations include:
The lymphatic system has several functions that affect the entire body. Systemic symptoms may include:
Rarely, Hodgkin lymphoma can trigger other syndromes in the body, called paraneoplastic syndromes. It occurs when an abnormal immune system attacks healthy cells of the nervous system. It can result in difficulty with motor skills like walking or swallowing, and changes in mental state.
Adult Hodgkin lymphoma treatment (PDQ)—patient version. National Cancer Institute website. Available at: https://www.cancer.gov/types/lymphoma/patient/adult-hodgkin-treatment-pdq. Updated April 12, 2017. Accessed March 30, 2018.
Hodgkin lymphoma. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/hematology-and-oncology/lymphomas/hodgkin-lymphoma. Updated October 2012. Accessed March 30, 2018.
Hodgkin lymphoma (HL). EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114957/Hodgkin-lymphoma-HL . Updated November 22, 2017. Accessed March 30, 2018.
Signs and symptoms. Leukemia & Lymphoma Society website. Available at:
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Accessed March 30, 2018.
Signs and symptoms of Hodgkin lymphoma. American Cancer Society website. Available at: https://www.cancer.org/cancer/hodgkin-lymphoma/detection-diagnosis-staging/signs-and-symptoms.html. Updated March 28, 2017. Accessed March 30, 2018.
Last reviewed March 2018 by EBSCO Medical Review Board Mohei Abouzied, MD, FACP
Last Updated: 2/29/2016
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