Supplement Forms/Alternate Names:



Corydalis is an herb that is native to China. It has been used to ease pain in the body. Corydalis can be taken as a pill, powder, or extract. It can also be made into a tea.


2 to 10 grams once daily

What Research Shows

May Be Effective

  • Knee osteoarthritis —may ease pain when used with standard treatmentA1
  • Rheumatoid arthritis —may ease symptoms when used with standard treatmentB1

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It may be safe for most people to take corydalis. Not enough studies have been done to say whether it is safe to take for a long period or by those who are pregnant or breastfeeding.


Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.



A. Knee Osteoarthritis

A1. Zuo C, Yin G, et al. [Controlled clinical study on compound Decumbent Corydalis Rhizome and diclofenac in treatment of knee osteoarthritis]. Zhongguo Zhong Yao Za Zhi. 2015;40(1):149-153.

B. Rheumatoid Arthritis

B1. Zuo C, Chen YT, et al. [Clinical efficacy of Corydalis composite combined with methotrexate in treating rheumatoid arthritis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009;29(11):1023-1025.

Last reviewed February 2020 by EBSCO NAT Review Board Eric Hurwitz, DC