Diindolylmethane
Introduction
Diindolylmethane is a compound found in cruciferous vegetables. These vegetables include broccoli, cabbage, kale, and brussels sprouts. The compound has been used to lower markers of cancer. It can be taken as a pill or by eating cruciferous vegetables.
Dosages
150 milligrams twice daily
What Research Shows
Not Enough Data to Assess
- Cervical dysplasia 1, 2
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Safety Notes
It is likely safe to take diindolylmethane for a short time. Not enough studies have been done to say whether it is safe to take for a long period.
Interactions
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.
References►
1. Del Priore G, Gudipudi DK, et al. Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia. Gynecol Oncol. 2010 Mar;116(3):464-467.
2. Castañon A, Tristram A, et al. Effect of diindolylmethane supplementation on low-grade cervical cytological abnormalities: double-blind, randomised, controlled trial. Br J Cancer. 2012 Jan 3;106(1):45-52.
Last reviewed February 2020 by EBSCO NAT Review Board Eric Hurwitz, DC Last Updated: 5/27/2020