Arsenic toxicity occurs when a person is exposed to arsenic. Arsenic is a naturally occurring element in the earth’s crust. It has no smell or taste. If you suspect you have been exposed to arsenic, contact your doctor immediately.
There are two primary forms of arsenic:
Inorganic arsenic is usually more harmful than organic arsenic.
Arsenic occurs naturally in soil and minerals, and may enter the air, water, and soil. It is also used:
Arsenic toxicity may occur when a person is exposed to toxic amounts of arsenic due to:
Anyone can develop arsenic toxicity as a result of arsenic exposure. But certain people are more likely to be exposed to arsenic. The following factors increase your chances of being exposed to arsenic. If you have any of these risk factors, tell your doctor:
In addition, children may be more susceptible than adults to the health effects of arsenic. There is some evidence that arsenic exposure may harm pregnant women and their unborn babies.
Symptoms of arsenic exposure include:
In addition, people exposed to arsenic may be at a greater risk of developing heart disease.
Your doctor will:
It can be difficult to make a diagnosis of arsenic poisoning because symptoms are so varied. If you have concerns about arsenic causing symptoms in yourself or a family member, talk to your doctor. The following tests may be done:
There is no effective treatment for arsenic toxicity. There is increasing evidence that chelation therapy may benefit some arsenic poisoned persons. Chelation therapy involves putting a chemical, or chelating agent, into the bloodstream. The chelating agent combines with a toxin to help remove it from the body. Chelating agents may be given by pill or by injection.
If chelation is not indicated or is ineffective, your treatment will be designed to help manage and relieve your symptoms. Treatment may include IV hydration, for example.
To help reduce your chances of getting arsenic toxicity, take the following steps:
Agency for Toxic Substances and Disease Registry
Centers for Disease Control and Prevention
US Environmental Protection Agency
Canadian Centre for Occupational Health and Safety
Arsenic and drinking water from private wells. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov... . Updated May 3, 2010. Accessed April 2, 2013.
Arsenic poisoning. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/ . Updated December 4, 2012. Accessed April 2, 2013.
Chen Y, Graziano JH, Parvez F, et al. Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study. BMJ. 2011;342:d2431.
Fauci A. Harrison’s Principles of Internal Medicine . 16th ed. New York, NY: McGraw Hill; 2005.
Fourth national report on exposure to environmental chemicals. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/exposurereport/pdf/FourthReport.pdf . Published 2009. Accessed April 2, 2013.
ToxFAQs for arsenic. Agency for Toxic Substances and Disease Registry website. Available at: http://www.atsdr.cdc.gov/tfacts2.html . Updated July 20, 2010. Accessed April 2, 2013.
Last reviewed November 2012 by Igor Puzanov, MD
Last Updated: 11/26/2012