Depression can be devastating to family relationships, friendships, and the ability to work or go to school. Symptoms of depression vary a great deal from person to person. Some people have only a few symptoms, while others have many.

Symptoms can change over time and may include:

• Persistent feelings of sadness, emptiness, or hopelessness
• Feeling guilty, worthless, or helpless
• Loss of interest in hobbies and activities
• Loss of interest in sex
• Feeling tired
• Trouble concentrating, remembering, or making decisions
• Trouble sleeping, waking up too early, or oversleeping
• Eating more or less than usual
• Weight gain or weight loss
• Restlessness, irritability, or anxiety
• Physical symptoms that defy standard diagnosis and do not respond well to medical treatments
• Thoughts of death or suicide (with or without suicide attempts)