Print PDF | Print | Search | Send-to-Friend | Health Library Home

The following information is an educational aid only. It is not intended as a medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Domperidone

(dom PE ri done)


Canadian Brand Names
Apo-Domperidone®; Dom-Domperidone; Mylan-Domperidone; Novo-Domperidone; Nu-Domperidone; PHL-Domperidone; PMS-Domperidone; RAN™-Domperidone; ratio-Domperidone
Mexican Brand Names
Motilium; Seronex
Pharmacologic Category
Dopamine Antagonist, Peripheral; Gastrointestinal Agent, Prokinetic
What key warnings should I know about before taking this medicine?

This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to domperidone or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Gastrointestinal bleeding, hole in the gastrointestinal tract, intestinal blockage, or tumor on pituitary gland.

What is this medicine used for?

• This medicine is used in patients receiving tube feedings who have high residuals.

• This medicine is used to prevent nausea and vomiting caused by medicines for Parkinson's disease.

• This medicine is used to treat heartburn.

• This medicine is used to treat poor stomach emptying.

How does it work?

• Domperidone increases gastric emptying of food and decreases symptoms of nausea, vomiting, heartburn, and fullness.

How is it best taken?

• Take this medicine 15-30 minutes before meals and at bedtime.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What are the precautions when taking this medicine?

• If you have breast cancer, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• If you have low potassium levels or if you are taking a water pill, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid alcohol, quit smoking, elevate head of the bed, avoid large meals before bed, lose weight, and avoid fatty foods, chocolate, caffeine, or citrus.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Headache.

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Fast heartbeat.

• Severe dizziness or passing out.

• Any rash.

• No improvement in condition or feeling worse.

How should I store this medicine?

• Store at room temperature.

• Protect from light.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• You may report side effects to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.


Created: 2005-04-07 16:35:42.0

Modified: 2009-12-09 09:08:29.0

Lexi-PALSTM © (1977)-(2010) Lexi-Comp, Inc. All rights reserved.