Cushing syndrome is a hormone disorder. Cortisol, in normal doses, helps the body manage stress and infection. However, high levels over a long period of time can cause several health problems.
Prolonged or excess exposure to cortisol may be caused by:
Pituitary and Adrenal Glands
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Factors that may increase your chance of Cushing syndrome include using corticodsteroids to treat diseases, such as:
Cushing syndrome may cause:
You will be asked about your symptoms and medical history. A physical exam will be done. Tests may be done to determine the level of cortisol and find a cause.
Blood tests, urine tests, and saliva tests may be done.
Imaging tests evaluate the pituitary and adrenal glands, and other internal structures. These may include:
Treatment of Cushing syndrome depends on the cause. Talk with your doctor about the best treatment plan for you. Options include:
Work with your doctor to keep your use of corticosteroid drugs to a minimum.
Cushing's Support and Research Foundation
Family Doctor—American Academy of Family Physicians
The College of Family Physicians of Canada
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Updated April 2012. Accessed March 5, 2018.
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Last reviewed March 2018 by
EBSCO Medical Review Board
Alan Drabkin, MD
Last Updated: 2/17/2016