Pronounced: YOO-ingz sar-KOH-muh
Ewing's sarcoma is a type of cancer that occurs in the bone or soft tissue. Areas that are commonly affected include the pelvis, thigh, lower leg, upper arm, and chest wall. Prognosis depends on the location of the tumor and whether it has spread to other parts of the body.
It is thought that Ewing’s sarcoma is caused by a problem with the chromosomes. Certain chromosomes (numbers 11 and 22) are rearranged. This rearrangement causes some genes to be fused together.
Some factors that increase the risk include:
Symptoms may include:
These symptoms may be caused by other, less serious conditions. If your child has any of these, talk to the doctor.
The doctor will ask about your child’s symptoms and medical history. A physical exam will also be done. Tests may include:
Your child will work with a team of doctors. Talk with the team to determine the best treatment options for your child. These options include:
Surgery may also be used to remove the tumor, as well as rebuild the affected bone. Depending on the location of the tumor, a bone graft or prosthesis (artificial limb) may be needed. There are special types of prostheses that expand as the bone grows. Sometimes several surgeries are needed to make sure the limb functions properly.
Stem cells produce red and white blood cells, as well as platelets. Because of the cancer and the treatments, your child’s stem cells may be damaged. During a stem cell transplant, new cells are injected into a vein, and travel to the bone cavities.
Your child will need to work with a team of therapists, such as:
The team will also provide support as your child goes through treatment.
United States National Library of Medicine
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Children’s Hospital Boston. Ewing’s sarcoma. Children’s Hospital Boston website. Available at: http://www.childrenshospital.org/az/Site852/mainpageS852P0.html . Accessed June 30, 2010.
Children’s Hospital of Wisconsin. Ewing sarcoma. Children’s Hospital of Wisconsin website. Available at: http://www.chw.org/display/PPF/DocID/22003/router.asp . Accessed June 30, 2010.
DynaMed Editorial Team. Ewing sarcoma. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated June 29 , 2010. Accessed June 30, 2010.
Kohnle D, Kellicker P. Ewing’s sarcoma. EBSCO Health Library website. Available at: http://www.ebscohost.com/healthLibrary/ . Updated September 30, 2010. Accessed June 30, 2010.
Nelson Textbook of Pediatrics, 18th Edition. RM Kliegman, HB Jenson, RE Behrman, BF Stanton, Editors. Saunders Elsevier, Philadelphia PA, 2007.
Last reviewed June 2012 by Kari Kassir, MD
Last Updated: 06/06/2012