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Lobular Carcinoma in Situ

(LCIS)

Definition

Lobules are the part of the breast that produces milk. Lobular carcinoma in situ (LCIS) is when there are abnormal cells in the lobules of the breast. These abnormal cells do not grow in an uncontrolled way or spread to other parts of the body like cancer. But, LCIS is a risk factor for future breast cancer.

Causes    TOP

It is not clear what causes LCIS. It is likely due to a change in a gene.

Risk Factors    TOP

LCIS is more common in premenopausal women who are between 40-50 years old.

Symptoms    TOP

LCIS does not have symptoms.

Diagnosis    TOP

LCIS does not appear on imaging tests. It can’t be felt during a breast exam. It is usually found during a biopsy of other nearby breast tissue.

Treatment    TOP

LCIS does not require treatment.

Your doctor will monitor your breast for changes with:

  • A physical and breast exam every 6-12 months
  • A yearly mammogram

Prevention    TOP

Take these steps to reduce your overall risk of breast cancer:

  • Exercise regularly.
  • Eat a healthful diet.
  • Maintain a healthy weight.
  • Avoid or limit alcohol. This means 1 drink or less a day for women and 2 drinks or less a day for men.
  • Follow your doctor’s guidelines for regular breast cancer screening.

RESOURCES:

American Cancer Society
https://www.cancer.org
National Cancer Institute
https://www.cancer.gov

CANADIAN RESOURCES:

Canadian Cancer Society
http://www.cancer.ca

References:

LCIS—lobular carcinoma in situ. Breast Cancer website. Available at:
...(Click grey area to select URL)
Update February 18, 2017. Accessed January 29, 2018.
Lobular carcinoma in situ. EBSCO DynaMed Plus website. Available at: http://www.dynamed.... Updated August 18, 2016. Accessed January 29, 2018.
Lobular carcinoma in situ (LCIS). American Cancer Society website. Available at: https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions/lobular-carcinoma-in-situ.html. Updated September 20, 2017. Accessed January 29, 2018.
Venkitaraman, R. Lobular neoplasia of the breast. Breast J. 2010;16(5):519-528.
Last reviewed December 2017 by EBSCO Medical Review Board Mohei Abouzied, MD, FACP
Last Updated: 5/21/2018

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