|CRDAMC Homepage | CRDAMC Library Phone #: (254) 288-8366 | CRDAMC Library Fax #: (254) 288-8368|
Pronounced: Het-toro-toe-pik Oss-if-a-kay-shun
by Patricia Griffin Kellicker, BSN
Heterotopic ossification (HO) is the growth of bone in abnormal places like soft tissue. It can occur anywhere in the body. The hip, knees, shoulders, and elbows are the most common locations. This condition can vary from minor to large growths.
The exact cause of HO is unknown. There may be a genetic link to the development of this condition.
Risk Factors TOP
Factors that may increase your chance of developing HO include:
Symptoms vary based on the severity and site of the bone growth. HO may cause:
You will be asked about your symptoms and medical history. A physical exam will be done. You may be referred to a specialist. An orthopedic doctor focuses solely on problems of the bones and joints.
Your bodily fluids may be tested. This can be done with:
Images may be taken of your bodily structures. This can be done with:
Talk with your doctor about the best plan for you. Options vary based on the scope of the disease, and include the following:
Therapy is an important part of treatment. Range of motion exercises will help to maintain mobility. It can also keep the disease from getting worse. Therapy may also include some stretching and strength training.
Your doctor may prescribe:
Surgery may be used to remove the abnormal bone and increase range of motion. Radiation and medications are often given after surgery, since the disease can recur.
HO is not well understood. If you have any of the risk factors above, talk to your doctor about any symptoms you may have. Discuss whether you need to take preventive measures, which are similar to treatments.
Ortho Info—American Academy of Orthopaedic Surgeons
Spinal Cord Injury Information Network
Canadian Orthopaedic Association
Canadian Orthopaedic Foundation
Black DL, Smith JD, Dalziel RE, Young DA, Shimmin A. Incidence of heterotopic ossification after hip resurfacing. Australian and New Zealand Journal of Surg. 2007;77:642-647.
Pape HC, Marsh S, Morley JR, Krettek C, Giannoudis PV. Current concepts in the development of heterotopic ossification. Journal of Bone and Joint Surgery. 2004;86(6):783-7.
Spinal cord injury—InfoSheet #12. Spinal Cord Injury Information Network website. Available at:
...(Click grey area to select URL)
Published June 1997. Accessed May 9, 2016.
Zychowicz ME. Pathophysiology of heterotopic ossification. Orthop Nurs. 2013;32(3):173-177.
Last reviewed June 2016 by Michael Woods, MD
Last Updated: 6/1/2013
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.