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Acute Tubular Necrosis
by Krisha McCoy, MS
Acute tubular necrosis is damage to the tubule cells (tiny tube-shaped cells) in the kidney that results in acute kidney failure. This is a potentially serious condition that requires medical care.
Acute tubular necrosis can be caused by:
Risk Factors TOP
Factors that may increase your chance of acute tubular necrosis include:
Acute tubular necrosis may cause:
You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids and tissues may be tested. This can be done with:
Images may be taken of the kidneys and surrounding structures. This can be done with:
Talk with your doctor about the best treatment plan for you. Treatment will focus on treating the conditions that are causing damage. Good nutrition and proper fluid intake will also help reduce stress on the kidneys during recovery. Treatment options may also include:
Dialysis is a process that uses a machine to assist or take over the work of your kidneys. The blood flows from catheters to a machine that removes wastes and returns it back to the body.
Certain medications may reduce the need for dialysis in some people.
Acute tubular necrosis is sometimes the result of an accident. If you have kidney disease or a history of kidney problems, follow your doctor's instructions after surgical procedures or imaging tests that required injections of contrast.
Family Doctor—American Academy of Family Physicians
National Institute of Diabetes and Digestive and Kidney Diseases
Kidney Foundation of Canada
Acute tubular necrosis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated February 12, 2016. Accessed June 1, 2016.
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Esson ML, Schrier RW. Diagnosis and treatment of acute tubular necrosis. Ann Intern Med. 2002;137(9):744-52.
Gill N, Nally JV Jr, Fatica RA. Renal failure secondary to acute tubular necrosis: Epidemiology, diagnosis, and management. Chest. 2005;128(4):2847-2863.
Musso CG, Liakopoulos V, Ioannidis I, Eleftheriadis T, Stefanidis I. Acute renal failure in the elderly: Particular characteristics. Int Urol Nephrol. 2006;38(3-4):787-793.
Tepel M, van der Giet M, Schwarzfeld C, Laufer U, Liermann D, Zidek W. Prevention of radiographic-contrast reductions in renal function by acetylcysteine. N Engl J Med. 2000;343(3):1448-1457.
Last reviewed June 2016 by Adrienne Carmack, MD
Last Updated: 5/11/2013
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