|CRDAMC Homepage | CRDAMC Library Phone #: (254) 288-8366 | CRDAMC Library Fax #: (254) 288-8368|
Genes Start Mutating Soon After Life Begins, Study Finds
-- Robert Preidt
THURSDAY, Dec. 7, 2017 (HealthDay News) -- Hundreds of minor genetic mutations start to form in the cells of an embryo soon after conception, researchers have discovered.
The Yale University and Mayo Clinic scientists said that many of these mutations occur as sex cells are forming in the embryo. That means they can become part of the embryo's genome and be passed on to the next generation.
"This opens up a larger perspective on human development," study author Flora Vaccarino, a neuroscience professor at Yale, said in a Yale news release. "Some of our genome does not come from our parents."
These early genetic mutations are also similar to those found in cancers, according to the researchers. They said this suggests that cancers can occur as a normal byproduct of cell division.
They added that their findings may provide new insight into the causes of neurodevelopmental disorders such as schizophrenia or autism. These conditions are primarily the result of genetic abnormalities, but no single gene inherited by parents has been found to cause a large number of cases.
The study may also help explain why one identical twin might have a genetic disorder while the other is healthy, or why some members of a family who carry a disease-causing mutation do not get sick, the researchers said.
The findings were published Dec. 7 in the journal Science.
The U.S. National Institute of General Medical Sciences has more on https://www.nigms.....
Copyright © 2017 http://www.healthday.com/. All rights reserved.
The information in this article, including reference materials, are provided to you solely for educational or research purposes. Information in reference materials, are not and should not be considered professional health care advice upon which you should rely. Health care information changes rapidly and consequently, information in this article may be out of date. Questions about personal health should always be referred to a physician or other health care professional.
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.