Non-infective endocarditis is the growth of blood clots on the valves and inner walls of the heart. They can damage the heart. The growths can also break off and block blood flow in the brain, lungs, or other areas of the body.
This condition is often caused by health problems that:
Let the blood clot too easily
Damage areas of the heart valve—such as an illness or birth defect
The goal is to stop the growth of more clots. This will help to prevent problems like a stroke. Medicine can make it harder for blood to clot. This can stop clots, but also increase the risk of bleeding.
Problems that raise the risk of blood clots will also need to be treated.
There are no known guidelines to prevent this condition.
Bussani R, De-Giogio F, et al. Overview and comparison of infectious endocarditis and non-infectious endocarditis: a review of 814 autoptic cases. In Vivo. 2019; 33(5): 1565–1572.
Nonbacterial thrombotic endocarditis (NBTE). EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/nonbacterial-thrombotic-endocarditis-nbte. Accessed September 1, 2021.
Noninfective endocarditis. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/cardiovascular-disorders/endocarditis/noninfective-endocarditis. Accessed September 1, 2021.
Last reviewed July 2021 by
EBSCO Medical Review Board
Nicole Meregian, PA
Last Updated: 9/1/2021
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