Laryngeal cancer is a disease in which cancer cells grow in the larynx. The larynx is a tube-shaped organ inside the neck that lies between the throat and the windpipe. Its main function is to produce sound for speaking.
Cancer occurs when cells in the body divide without control or order. Normally, cells divide in a regulated manner. If cells keep dividing uncontrollably when new cells are not needed, a mass of tissue forms, called a growth or tumor. The term cancer refers to malignant growths. These growths can invade nearby tissues. Cancer that has invaded nearby tissues can then spread to other parts of the body.
It is not clear exactly what causes these problems in the cells, but it is probably a combination of genetics and environment.
The physical exam, combined with all of your test results, will help to determine the type and stage of cancer you have. Staging is used to guide your treatment plan. Like other cancers, laryngeal cancer is staged from I-IV. Stage I is a very localized cancer, while stage IV indicates a spread to other parts of the body
Treatment depends on the stage of the cancer, and the size and location of the tumor. A combination of therapies may work best.
Surgery requires removal of a cancerous tumor and nearby tissue, and possibly nearby lymph nodes. Surgeries for laryngeal cancer include:
—This involves the removal of the larynx, including the vocal cords.
Partial laryngectomy—In this procedure, the surgeon removes the cancerous tissue while leaving as much of the vocal cords as possible.
—To help with breathing, a hole is made in the neck below the larynx. This may be temporarily necessary after surgery, or permanently placed in the case of laryngeal tumors that are too large to be removed.
Neck dissection—This involves the removal of the lymph nodes and part of the neck muscles to determine the spread of cancer.
the use of radiation to kill cancer cells and shrink tumors. This may be external radiation therapy, where the beam is directed at the tumor from a source outside the body.
is the use of drugs to kill cancer cells. This form of treatment may be given in many forms including pill, injection, and catheter. The drugs enter the bloodstream and travel through the body killing mostly cancer cells, but also some healthy cells. Chemotherapy may be used to reduce the size of a particularly large cancer.
General information about laryngeal cancer. National Cancer Institute website. Available at: https://www.cancer.gov/types/head-and-neck/patient/laryngeal-treatment-pdq. Updated September 27, 2017. Accessed October 9, 2017.
Laryngeal cancer. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/ear,-nose,-and-throat-disorders/tumors-of-the-head-and-neck/laryngeal-cancer. Updated January 2016. Accessed October 9, 2017.
Laryngeal and hypopharyngeal cancer. American Cancer Society website. Available at: https://www.cancer.org/cancer/laryngeal-and-hypopharyngeal-cancer.html. Accessed August 14, 2014.
2/3/2012 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T115660/Head-and-neck-cancer: Weller MD, Nankivell PC, McConkey C, Paleri V, Mehanna HM. The risk and interval to malignancy of patients with laryngeal dysplasia; a systematic review of case series and meta-analysis. Clin Otolaryngol. 2010;35(5):364-372.
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.