Trigeminal neuralgia (TN) is a problem with the trigeminal nerve. The nerve senses touch, pain, pressure, and temperature. It also helps make saliva and tears. TN causes severe, shooting pain along one side of the face.
The main symptom is searing pain on one side of the face. The pain may be felt inside the mouth or in the lips, cheek, chin, nostril, ear, or near the eye. Rarely, it may happen in the eye or forehead. Twitching or wincing may also happen.
The pain is sudden, severe, and stabbing. Even though the pain lasts less than 2 minutes, it can reoccur hundreds of times a day. Attacks can become totally disabling. They may seem to happen without notice or be triggered by temperature, washing, shaving, touching, or tickling the face. There may not be symptoms between attacks, except perhaps a dull ache.
Pain may come and go for days, weeks, months, or years. It may stop for months or years between attacks. Over time, the attacks may become more frequent and more severe.
Chole R, Pati R, Degwekar SS, Bhowate RR. Drug treatment of trigeminal neuralgia: a systematic review of the literature. J Oral Maxillfac Surg. 2007;65(1):40-45.
Gorgulho A, DeSalles A. Trigeminal neuralgia: impact of radiosurgery on the surgical treatment of trigeminal neuralgia. Surg Neurol. 2006;66(4):350-356.
Kalkanis SN, Eskandar EN, Carter BS, Barker FG 2nd. Microvascular decompression surgery in the United States, 1996-2000: mortality rates, morbidity rates, and the effects of hospital and surgeon volumes. Neurosurgery. 2003;52(6):1251-1261.
NINDS trigeminal neuralgia information page. National Institute of Neurological Disorders and Stroke website. Available at: https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Trigeminal-Neuralgia-Fact-Sheet. Updated May 10, 2017. Accessed June 25, 2018.
Pollock BE, Ecker RD. A prospective cost-effectiveness study of trigeminal neuralgia surgery. Clin J Pain. 2005;21(4):317-322.
Trigeminal neuralgia. American Academy of Neurological Surgeons website. Available at: http://www.aans.org/Patient%20Information/Conditions%20and%20Treatments/Trigeminal%20Neuralgia.aspx. Accessed June 25, 2018.
Last reviewed June 2018 by EBSCO Medical Review Board
Rimas Lukas, MD
Last Updated: 6/25/2018
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.