by Michelle Badash, MS
Gilbert syndrome is a genetic liver disorder. It causes levels of bilirubin to rise above normal levels. Bilirubin is a yellow chemical by-product of hemoglobin. Hemoglobin is the red pigment in blood cells that is usually excreted by the liver as bile.
Gilbert syndrome is usually caused by an inherited genetic abnormality. Symptoms occur when there is an interference with the liver enzyme that is important in the elimination of bilirubin. This causes the levels of bilirubin to increase in the blood, which may produce symptoms such as jaundice.
Risk Factors TOP
Factors that increase your risk of Gilbert syndrome include:
Often, there are no symptoms of Gilbert syndrome. However, people who do have symptoms may experience:
Your doctor will ask about your symptoms and medical history. A physical exam will be done. Tests may include:
No treatment is necessary for Gilbert syndrome. Usually, symptoms come and go.
American Liver Foundation
National Institute of Diabetes and Digestive and Kidney Diseases
Gilbert syndrome. American Liver Foundation website. Available at: http://www.liverfo... . Updated October 4, 2011. Accessed May 30, 2013.
Gilbert syndrome. Genetics Home Reference website. Available at: http://ghr.nlm.nih.gov/condition/gilbert-syndrome . Updated February 2012. Accessed May 30, 2013.
Last reviewed May 2013 by Kari Kassir, MD; Michael Woods, MD
Last Updated: 3/18/2013