Diabetic Foot UlcerDefinitionDiabetic foot ulcers are sores that occur on the feet of people with type 1 and type 2 diabetes. Up to 25% of people with diabetes develop foot problems. Diabetic foot ulcers usually occur on the bottom of the foot. They precede over 80% of leg amputations in the US. However, the sooner diabetic foot ulcers are treated, the better the outcome.
CausesDiabetes can damage the nerves of the legs and feet so that you may not feel a blister or sore when it begins to appear. If undetected, the sore may become larger and infected. This may lead to an amputation of a toe, a foot, or even a leg. Risk Factors TOPThe following factors increase your chance of developing diabetic foot ulcers. If you have diabetes and any of these risk factors, tell your doctor:
Symptoms TOPThese factors increase your chance of developing a foot ulcer. Tell your doctor if you have any of these risk factors:
Diagnosis TOPYour doctor will ask about your symptoms and medical history, and perform a physical exam. Your primary doctor may refer you to a foot specialist or podiatrist. Tests may include the following:
Treatment TOPTalk with your doctor about the best treatment plan for you. Treatment options include the following: MedicationRegranex gel is a medication approved by the Food and Drug Administration (FDA) for the treatment of diabetic foot ulcer. It has been shown to speed wound healing. No Weight-bearingKeeping pressure off the foot ulcer promotes healing. Sometimes special casts or boots are placed on the foot to “off-load” pressure from the ulcer. Wound CareCleanse the wound regularly and change the dressings often to prevent infection. AntibioticsAntibiotics may be used to prevent an infection. You may need to take the medicine for 4-6 weeks. Blood Sugar ControlInfected ulcers are likely to cause high blood sugar levels. High blood sugar levels lower immune response and prevent wound healing. Therefore, improved blood sugar control—with adjustments in diet or medications—aids in fighting infections and healing wounds. Sometimes insulin shots are needed in the short-term to achieve optimal blood sugar control. Skin GraftBioengineered skin graft or human skin graft can be used to treat diabetic foot ulcers which fail to heal with conventional treatments. Skin grafts have been shown to speed the healing process. SurgeryThe removal of dead tissue around the wound, or debridement, is often needed to clean the wound and promote healing. Bypass surgery to improve blood flow within the arteries of the legs may help with wound healing and spare amputations. As a last resort, amputation surgery may be needed to stop the spread of infection to the rest of the body. Hyperbaric Oxygen TherapyHyperbaric oxygen therapy appears to help reduce major amputations. People with nonhealing wounds are placed in a chamber. Pure oxygen is pumped into the chamber, which saturates the blood with oxygen. This oxygen-rich blood helps form new blood vessels, which helps the wound heal. If you are diagnosed with a diabetic foot ulcer, follow your doctor's instructions. Prevention TOPTo help reduce your chances of getting diabetic foot ulcers, take the following steps:
Foot Temperature MonitoringAccording to studies, if you are at high risk for diabetic foot ulcers, checking the temperature of your feet—using an infared skin thermometer—can reduce the number of ulcers. The TempTouch thermometer used in the study costs $150. Ask your doctor if you should check the temperature of your feet. RESOURCES:American Diabetes Association http://www.diabetes.org American Podiatric Medical Association http://www.apma.org CANADIAN RESOURCES:Canadian Diabetes Association http://www.diabetes.ca/ Podiatrists in Canada http://www.podiatrycanada.org/fin_pod.html References:
Andersen CA, Roukis TS: The diabetic foot.
Surg Clin North Am
. 2007;87:1149-1177.
Diabetic foot ulcer. DynaMed website. Available at:
http://www.ebscohost.com/dynamed/what.php
. Accessed September 20, 2005.
Frykberg RG. Diabetic foot ulcers: pathogenesis and management.
Am Fam Physician
. 2002;66:1655-1662.
Leung PC. Diabetic foot ulcers-a comprehensive review.
Surgeon
. 2007;5:219-231.
The Merck Manual of Diagnosis and Therapy
. 15th ed. Rahway, NJ: Merck Sharp and Dohme Research Laboratories; 1987.
Ndip A, Bowling F, Stickings D, Rayman G, Boulton AJ. The Diabetic Foot in 2008: an update from the 12th Malvern Diabetic Foot Meeting.
Int J Low Extrem Wounds.
2008;7:235-238.
Nelson EA, O’Meara S, Craig D, et al. A series of systematic reviews to inform a decision analysis for sampling and treating infected diabetic foot ulcers.
Health Tech Assess
. 2006;10.
Nelson EA, O’Meara S, Golder S, et al. Systematic review of antimicrobial treatments for diabetic foot ulcers.
Diabet Med
. 2006;23:348-359.
Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes.
JAMA
. 2005;293:217-228.
Your Medicare coverage: therapeutic shoes. Medicare website. Available at: http://www.medicare.gov/Coverage/Home.asp . Accessed September 25, 2005.
¹2/7/2008 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed/what.php
: Armstrong DG, Holtz-Neiderer K, Wendel C, Mohler MJ, Kimbriel HR, Lavery LA. Skin temperature monitoring reduces the risk for diabetic foot ulceration in high-risk patients.
Am J Med.
2007;120:1042-1046.
²2/7/2008 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed/what.php
: Lavery LA, Higgins KR, Lanctot DR, et al. Home monitoring of foot skin temperatures to prevent ulceration.
Diabetes Care.
2004;27:2642-2647.
Last reviewed September 2009 by Bridget Sinnott, MD, FACE Last Updated: 9/30/09 | ||