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Hypoxic Ischemic Encephalopathy—NewbornCerebral Hypoxia—Newborn; HIE—Newborn; Neonatal HIEhye-POK-sic is-KEM-ik en-sef-a-lo-path-ee
by Cynthia M. Johnson, MA DefinitionHypoxic ischemic encephalopathy (HIE) is injury to the brain because of a lack of oxygen. The injury can lead to a range of disabilities. A severe injury can lead to death.
CausesBrain cells can start to die after 4 minutes without oxygen. This may happen because of poor blood flow to the brain or low levels of oxygen in the blood. In a newborn, it is often caused by a problem at birth. Some HIE in newborns may be caused by a disease or illness. Risk FactorsFactors before or during labor and delivery that increase the risk of HIE include:
SymptomsSymptoms can vary from mild to severe. They may include:
Some symptoms such as learning or development delays may not appear until the child is older. DiagnosisBabies are observed after birth. An APGAR score will check signs of health. A baby with HIE will have lower APGAR scores. An MRI scan may be done. This will help to show or track damaged areas of the brain. The doctor will use these results as well as details about the birth to diagnose HIE. Other tests may be needed if a cause is not clear. This may include blood tests. TreatmentImmediate care will make sure the brain is getting enough oxygen. Support may include:
The long-term effects of HIE will depend on the area of the brain and amount of damage. Some may have severe disabilities. Others may be mild and not apparent until the baby is older. Early intervention is important. Supportive care will help to minimize the effect of the injury. Assistive devices, exercises, and learning aids may be needed. PreventionIn most cases, HIE is sudden and cannot be prevented. RESOURCES:Family Doctor—American Academy of Family Physicians http://www.familydoctor.org Healthy Children—American Academy of Pediatrics http://www.healthychildren.org CANADIAN RESOURCES:About Kids Health—The Hospital for Sick Children http://www.aboutkidshealth.ca Health Canada http://www.hc-sc.gc.ca References:Douglas-Escobar M, Weiss MD. Hypoxic-ischemic encephalopathy: a review for the clinician. JAMA Pediatr. 2015 Apr;169(4):397-403. Hypoxic-ischemic encephalopathy. EBSCO Nursing Reference Center website. Available at: ...(Click grey area to select URL) Updated February 23, 2018. Accessed January 11, 2019. Hypoxic ischemic encephalopathy of the newborn. London Health Sciences Centre website. Available at: ...(Click grey area to select URL) Updated January 2010. Accessed January 11, 2019. Neonatal hypoxic-ischemic encephalopathy (HIE). EBSCO DynaMed website. Available at: http://www.dynamed.... Updated July 30, 2018. Accessed January 11, 2019. Last reviewed September 2020 by
EBSCO Medical Review Board
Chelsea Skucek, MSN, BS, RNC-NIC Last Updated: 12/18/2020 | |