Mitral Valve Prolapse
(MVP; Floppy Valve Syndrome; Barlow's Syndrome; Click-Murmur Syndrome)
by Michelle Badash, MS
Mitral valve prolapse (MVP) is a common, usually benign heart disorder. The mitral valve controls blood flow between the upper and lower chambers on the left side of the heart. Normally, blood should only flow from the upper chamber into the lower chamber. In MVP, the valve flaps do not work properly. Part of the valve balloons into the atrium, which may be associated with blood flowing in the wrong direction or leaking back into the lower chamber.
In most cases, the cause of MVP is unknown. In some cases, it appears to be an inherited genetic condition.
MVP is more common in women and most often appears between the ages of 14 and 30 years old. Other factors that may increase your chance of MVP include:
People with mitral valve prolapse often do not have symptoms. If symptoms do occur, they may include one or more of the following:
Mitral valve prolapse can be heard through a stethoscope. A small blood leakage will sound like a murmur. When the mitral valve balloons backward, it may produce a clicking sound. Both murmurs and clicks are signs of MVP. An echocardiogram can confirm the diagnosis. You may also be asked to wear a Holter monitor for a day or 2 to record the electrical activity of your heart.
In most cases, no treatment is necessary. Although no longer routinely recommended, you may need to take antibiotics prior to some dental and medical procedures. This is to prevent heart infections. Ask your doctor if you will need to take antibiotics.
If symptoms include chest pain, anxiety, or panic attacks, a beta-blocker medication can be prescribed. Ask your doctor whether you may continue to participate in your usual physical activities.
In very rare cases, the blood leakage may become severe. In these few cases, the mitral valve may need to be surgically repaired or replaced.
There are no current guidelines for preventing MVP of unknown or genetic origin. However, you may be able to prevent symptoms through certain lifestyle changes:
American Heart Association
National Heart, Lung, and Blood Institute
Canadian Cardiovascular Society
The College of Family Physicians of Canada
Antibiotic prophylaxis for heart patients. Mouth Healthy—American Dental Association website. Available at:
...(Click grey area to select URL)
Accessed September 14, 2020.
Infective endocarditis. EBSCO DynaMed website. Available at: http://www.dynamed.... Accessed September 14, 2020.
Mitral valve prolapse (MVP). EBSCO DynaMed website. Available at: http://www.dynamed.... Accessed September 14, 2020.
Shipton B and Wahba H. Valvular heart disease: review and update. Am Fam Physician. 2001;63(11):2201-2208.
Last reviewed September 2020 by EBSCO Medical Review Board Michael J. Fucci, DO, FACC
Last Updated: 9/15/2020