Piperacillin and tazobactam injection is used to treat pneumonia and skin, gynecological, and abdominal (stomach area) infections caused by bacteria. Piperacillin is in a class of medications called penicillin antibiotics. It works by killing bacteria that cause infection. Tazobactam is in a class called beta-lactamase inhibitor. It works by preventing bacteria from destroying piperacillin.
Antibiotics such as piperacillin and tazobactam injection will not work for colds, flu, or other viral infections. Taking or using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Piperacillin and tazobactam injection comes as a powder to be mixed with liquid and injected intravenously (into a vein). It is usually given every 6 hours, but children 9 months of age and older may receive it every 8 hours. The length of treatment depends on your general health, the type of infection you have, and how well you respond to the medication. Your doctor will tell you how long to use piperacillin and tazobactam injection. After your condition improves, your doctor may switch you to another antibiotic that you can take by mouth to complete your treatment.
You may receive piperacillin and tazobactam injection in a hospital, or you may administer the medication at home. If you will be receiving piperacillin and tazobactam injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.
You should begin to feel better during the first few days of treatment with piperacillin and tazobactam injection. If your symptoms do not improve or if they get worse, call your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using piperacillin and tazobactam injection,
Unless your doctor tells you otherwise, continue your normal diet.
Piperacillin and tazobactam injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
Piperacillin and tazobactam injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site ) or by phone (1-800-332-1088).
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to piperacillin and tazobactam injection.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving piperacillin and tazobactam injection. If you have diabetes, piperacillin and tazobactam injection can cause false results with certain urine glucose tests. Talk to your doctor about using other glucose tests while using piperacillin and tazobactam injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: October 15, 2016.