(Anaphylactoid Purpura; HSP; Vascular Purpura)
How to Say It: Hen-awk-shern-line purr-purr-ah
by Cynthia M. Johnson, MA
Henoch-Schonlein purpura (HSP) is inflammation of the blood vessels in the skin and other organs. It results in a specific rash when the skin is involved. The rash looks like bruising or small dots, referred to as purpura.
HSP is caused by an abnormal reaction of the immune system. It attacks healthy blood vessels. It is not clear why this happens.
The change in the immune system may be triggered by:
HSP is most common in children who are 2 to 11 years of age. The risk of HSP is higher in people who have had:
Symptoms may last for 4 to 6 weeks and may include:
You will be asked about your symptoms and health history. A physical exam may be done.
Other tests may be:
HSP usually gets better on its own. Medicines may be used to:
There are no known guidelines to prevent HSP.
American Autoimmune Related Diseases Association
Family Doctor—American Academy of Family Physicians
Caring for Kids—Canadian Paediatric Society
College of Family Physicians of Canada
Henoch-Schonlein purpura. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/henoch-schonlein-purpura. Accessed October 23, 2020.
Henoch-Schonlein purpura. Family Doctor—American Academy of Family Physicians website. Available at: https://familydoctor.org/condition/henoch-schonlein-purpura. Accessed October 23, 2020.
Henoch-Schonlein purpura. GARD—Genetic and Rare Diseases Information Center website. Available at: https://rarediseases.info.nih.gov/diseases/8204/henochschonlein-purpura. Accessed October 23, 2020.
Hetland LE, Susrud KS, et al. Henoch-Schonlein Purpura: A Literature Review. Acta Derm Venereol. 2017 Nov 15;97(10):1160-1166.
Last reviewed September 2020 by EBSCO Medical Review Board Daniel A. Ostrovsky, MD
Last Updated: 5/19/2021
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