Tetanus, Diphtheria, and Pertussis Vaccine
by Krisha McCoy, MS
What does this vaccine help prevent?
This vaccine helps prevent:
What Is the Tdap Vaccine?
The Tdap vaccine contains diphtheria and tetanus toxoids, and acellular (small, purified pieces) pertussis germ.
It is given to children ≥ 7 years old, adolescents, and adults to protect against tetanus, diphtheria, and pertussis infections.
The vaccine is given as an injection, usually into the arm or thigh.
Who Should Get Vaccinated and When? TOP
Tdap is routinely recommended for children aged 11-12 years who have completed the DTaP series. Tdap can also be given to:
If you or your child has not been fully vaccinated against tetanus, diphtheria, and pertussis, talk to the doctor.
What Are the Risks Associated With the Pertussis Vaccine? TOP
Most people tolerate the vaccines without any trouble. The most common side effects are:
Uncommon symptoms include:
Acetaminophen is sometimes given to reduce pain and fever that may occur after getting a vaccine. In infants, the medication may weaken the vaccine's effectiveness. However, in children at risk for seizures, a fever lowering medication may be important to take. Discuss the risks and benefits of taking acetaminophen with your doctor.
Who Should Not Get Vaccinated? TOP
Most people should receive their vaccinations on schedule. However, individuals in whom the risks of vaccination outweigh the benefits include people who:
Talk with your doctor before getting the vaccine if you have:
What Other Ways Can Tetanus, Diphtheria, or Pertussis Be Prevented? TOP
The best way to prevent diphtheria is to get vaccinated.
Caring properly for wounds, including promptly cleaning them and seeing a doctor for medical care, can prevent a tetanus infection.
You can help prevent pertussis by keeping infants and other people at high risk away from infected people.
What Happens in the Event of a Pertussis Outbreak? TOP
In the event of a pertussis outbreak, all people who may have been exposed should be brought up to date with the vaccination. It is important to protect infants by isolating those who have the infection. Diagnosing the disease as quickly as possible can help control future outbreaks.
WHERE CAN I GET MORE INFORMATION?
American Academy of Pediatrics
National Immunization Program
Centers for Disease Control and Prevention
Centers for Disease Control and Prevention. FDA approval of expanded age indication for a tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine. MMWR Morb Mortal Wkly Rep. 2011;60(37):1279-1280.
Vaccinations for adults. Immunization Action Coalition website. Available at: http://www.immunize.org/catg.d/p4030.pdf . Accessed October 8, 2013.
Fisman DN, Tang P, Hauck T, Richardson S, Drews SJ, Low DE, Jamieson F. Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling. BMC Public Health. 2011;11:694.
Friedrich MJ. Research aims to boost pertussis control. JAMA. 2011;306(1):27-29.
Pertussis (whooping cough) vaccination. Centers for Disease Control and Prevention, National Immunization Program website. Available at: http://www.cdc.gov/vaccines/vpd-vac/pertussis/default.htm . Updated September 23, 2013. Accessed October 8, 2013.
Tdap vaccine: what you need to know. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/vaccines/hcp/vis/vis-statements/tdap.pdf . Published May 9, 2013. Accessed October 8, 2013.
1/31/2008 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php : Centers for Disease Control and Prevention. Recommended immunization schedules for persons aged 0-18 years—United States, 2008. MMWR. 2008;57;Q1-Q4. Centers for Disease Control and Prevention, MMWR website. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5701a8.htm . Updated January 10, 2008. Accessed January 28, 2008.
10/30/2009 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php : Prymula R, Siegrist C, Chlibek R, et al. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials. Lancet . 2009;374(9698):1339.
1/24/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php : Centers for Disease Control and Prevention (CDC). Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (tdap) vaccine from the advisory committee on immunization practices, 2010. MMWR Morb Mortal Wkly Rep. 2011;60(1):13-15.
11/4/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php : Centers for Disease Control and Prevention (CDC). Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant aged <12 months—Advisory Committee on Immunization Practices (ACIP), 2011. MMWR Morb Mortal Wkly Rep. 2011;60:1424-1426.
2/10/2014 DynaMed's Systematic Literature Surveillance
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Bridges C, Coyne-Beasley T. Advistory Committee on Immunization Practices recommended immunization schedules for adults aged 19 years or older: United States, 2014. Ann Intern Med. 2014;160(3):190-197.
Last reviewed June 2013 by Brian Randall, MD
Last Updated: 2/10/2014
Last Updated: 6/3/2013