(Agranulocytosis; Granulocytopenia; Granulopenia)
by Diana Kohnle
Neutropenia is an abnormally low number neutrophils in the blood. These are a type of white blood cell that helps fight infection.
There are 2 types:
Causes of neutropenia:
Defects with your genes cause the congenital type.
Acquired type causes:
Your chances of neutropenia are higher if you:
Most people don’t have symptoms. But, neutropenia can lead to an infection. This may cause:
You will be asked about your symptoms and medical history. You will be asked about recent infections, medical treatments, and medications. A physical exam will be done.
The doctor will ask about your symptoms and health history. You may have:
Care is based on the cause and how serious the condition is. It may involve:
Changing or avoiding medicines or toxins causing problems.
If you are at high risk for neutropenia, your doctor will watch you for any changes. Sometimes, medicines to stimulate white blood cell production are given in ahead of time.
Mouth Healthy—American Dental Association
NORD———National Organization for Rare Disorders
The College of Family Physicians of Canada
Boulton F, Cooper C, Hagenbeek A, Inskip H, Leufkens HG. Neutropenia and agranulocytosis in England and Wales: incidence and risk factors. Am J Hematol. 2003;72(4):248-254.
Neutropenia. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/hematology-and-oncology/leukopenias/neutropenia. Updated November 2016. Accessed July 13, 2018.
Neutropenia—approach to the patient. EBSCO DynaMed Plus website. Available at: http://www.dynamed... . Updated December 29, 2017. Accessed July 13, 2018.
Last reviewed May 2018 by EBSCO Medical Review Board Michael J. Fucci, DO, FACC
Last Updated: 7/13/2018
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