Vitamin B12 - Supplementation Possibly Helpful
Although primarily used on a short-term basis to treat attacks of gout, colchicine is increasingly being prescribed for longer periods as a gout preventive. This practice may heighten the chance of developing the nutritional deficiency discussed here.
Supplementation Possibly Helpful
Colchicine can impair intestinal absorption of vitamin B 12, so taking a B 12 supplement during extended colchicine therapy may be warranted.1
References [ + ]
1. Webb DI, Chodos RB, Mahar CQ, et al. Mechanism of vitamin B12 malabsorption in patients receiving colchicine. N Engl J Med 279: 845850, 1968.
Last reviewed December 2015 by EBSCO CAM Review Board