General Overview Restless legs syndrome (RLS) is a neurologic disorder characterized by unpleasant sensations in the legs and an irresistible urge to move them. The sensations are strongest at night. Special Topics Restless legs syndrome People with restless legs syndrome (RLS) often feel an intense urge to move their legs, particularly when sitting still or trying to fall asleep. Unlike those with nighttime leg cramps—a different condition—people with RLS don’t experience pain. Read more here. | Special Topics (Continued) Pregnancy and sleep: a contradiction in terms? Some women develop restless leg syndrome (RLS) during their third trimester of pregnancy. Read more here. Related Conditions Resources
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