| Drug Interactions:

Clonidine

Coenzyme Q10 (CoQ10) - Supplementation Possibly Helpful | Yohimbe - Probable Dangerous Interaction | Coleus forskohlii - Theoretical Interaction

Trade Names
  • Catapres

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Clonidine is often used to reduce blood pressure as well as to counter symptoms that occur during withdrawal from alcohol and other addictive substances.

 

 

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Coenzyme Q10 (CoQ10)

Supplementation Possibly Helpful

There is some evidence that clonidine might impair the body's ability to manufacture the substance coenzyme Q ₁₀ (CoQ ₁₀).¹  However, it has not yet been shown that CoQ ₁₀ supplements offer any particular benefit to those taking this medication.

 

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Yohimbe

Probable Dangerous Interaction

If you are taking clonidine, it is not safe to take yohimbe.² 

 

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Coleus forskohlii

Theoretical Interaction

The herb Coleus forskohlii relaxes blood vessels and might have unpredictable effects if combined with clonidine.

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References [ + ]

1. Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q ₁₀ -enzymes by clinically used anti-hypertensive drugs. Res Commun Chem Pathol Pharmacol 12(3): 533–540, 1975.

2. Brinker F. Herb contraindications and drug interactions, 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998: 140–141.

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Last reviewed December 2015 by EBSCO CAM Review Board
Last Updated: 12/15/2015

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