Medication for Gallstones

Bile Acids

• Ursodeoxycholic acid
• Chenodeoxycholic acid

Bile acids are only used to dissolve cholesterol gallstones when a person with cholesterol stones has a serious medical condition that prevents surgery. It may take months or years before all the stones dissolve completely.

Note: Do not take ursodeoxycholic acid with aluminum-containing antacids, such as AlternaGEL or Maalox Advanced Regular Strength, because the aluminum may interfere with the action of ursodeoxycholic acid.

A possible side effect is mild diarrhea.

Pain Medications

• Diclofenac
• Ketorolac

These medications are prescription NSAIDs used to relieve pain caused by gallstones.

Possible side effects include:

• Nausea
• Vomiting
• Diarrhea or constipation
• Lightheadedness
• Drowsiness

When to Contact Your Doctor

Severe abdominal pain, stomach pain, or severe nausea and vomiting may be a sign that you have another medical problem or that your gallstones require a different treatment.

Special Considerations

If you are taking medications, follow these general guidelines:

• Take the medication as directed. Do not change the amount or the schedule.
• Ask what side effects could occur. Report them to your doctor.
• Talk to your doctor before you stop taking any prescription medication.
• Plan ahead for refills if you need them.
• Do not share your prescription medication with anyone.
• Medications can be dangerous when mixed. Talk to your doctor if you are taking more than one medication, including over-the-counter products and supplements.