Cold sores have very recognizable features. They are most often diagnosed by physical exam and by your medical history. If your doctor is not sure, a sample of the fluid or tissue from the blister may be taken. A blood sample may also be taken for testing.
Testing may include any of the following:
Cold sores. Nemours Kids Health website. Available at:
...(Click grey area to select URL)
Accessed January 29, 2021.
Herpes simplex. American Academy of Dermatology website. Available at: https://www.aad.org/public/diseases/contagious-skin-diseases/herpes-simplex. Accessed January 29, 2021.
Oral herpes. EBSCO DynaMed website. Available at: http://www.dynamed.com/topics/dmp~AN~T115104/Oral-herpes . Accessed January 29, 2021.
Last reviewed March 2020 by
EBSCO Medical Review Board
David L. Horn, MD, FACP
Last Updated: 1/29/2021