Meropenem and vaborbactam injection is used to treat serious urinary tract infections, including kidney infections, that are caused by bacteria. Meropenem is in a class of medications called carbapenem antibiotics. It works by killing bacteria. Vaborbactam is in a class of medications called beta-lactamase inhibitors. It works by preventing bacteria from destroying meropenem.
Antibiotics such as meropenem and vaborbactam injection will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Meropenem and vaborbactam injection comes as a powder to be mixed with liquid and injected intravenously (into a vein). It is infused (injected slowly) intravenously over a period of 3 hours every 8 hours for up to 14 days. The length of treatment depends on your general health and how well you respond to the medication. Your doctor will tell you how long to use meropenem and vaborbactam injection. After your condition improves, your doctor may switch you to another antibiotic that you can take by mouth to complete your treatment.
You may receive meropenem and vaborbactam injection in a hospital, or you may administer the medication at home. If you will be receiving meropenem and vaborbactam injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions and ask your healthcare provider if you have any questions.
You should begin to feel better during the first few days of treatment with meropenem and vaborbactam injection. If your symptoms do not improve or if they get worse, call your doctor.
Use meropenem and vaborbactam injection until you finish the prescription, even if you feel better. If you stop using meropenem and vaborbactam injection too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before using meropenem and vaborbactam injection,
Unless your doctor tells you otherwise, continue your normal diet.
Meropenem and vaborbactam injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, stop using meropenem and vaborbactam injection and call your doctor immediately or get emergency medical treatment:
Meropenem and vaborbactam injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( Web Site) or by phone (1-800-332-1088).
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at Web Site. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to meropenem and vaborbactam injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.