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Henoch-Schonlein purpura (HSP) is inflammation of the blood vessels in the skin and other organs. It results in a specific rash when the skin is involved. The rash looks like bruising or small dots, referred to as purpura.
HSP is caused by an abnormal reaction of the immune system. It attacks healthy blood vessels. It is not clear why this happens.
The change in the immune system may be triggered by:
HSP is most common in children aged 2 to 11 years old, but it can happen at any age. Your chances are higher if you had:
Symptoms may last for 4 to 6 weeks and may include:
The doctor will ask about your symptoms and health history. You may have:
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HSP usually gets better on its own. Your doctor may give you medicines if you are having problems. Medicines are used to:
There is no way to prevent HSP since the cause is unknown.
American Autoimmune Related Diseases Association
Family Doctor—American Academy of Family Physicians
Caring for Kids—Canadian Paediatric Society
College of Family Physicians of Canada
Dillon MJ. Henoch-Schonlein purpura (treatment and outcome). Cleve Clin J Med. 2002;69(Suppl 2):SII121-SII123.
Henoch-Schonlein purpura. EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T113911/Henoch-Schonlein-purpura. Updated January 29, 2018. Accessed July 10, 2018.
Henoch-Schonlein purpura. Family Doctor—American Academy of Family Physicians website. Available at: https://familydoctor.org/condition/henoch-schonlein-purpura. Updated July 24, 2017. Accessed July 10, 2018.
Henoch-Schonlein purpura. GARD—Genetic and Rare Diseases Information Center website. Available at: https://rarediseases.info.nih.gov/diseases/8204/henochschonlein-purpura. Updated April 14, 2013. Accessed July 10, 2018.
Reamy BV, Williams PM, Lindsay TJ. Henoch-Schonlein purpura. Am Fam Physician. 2009;80(7):697-704.
Saulsbury FT. Epidemiology of Henoch-Schonlein purpura. Cleve Clin J Med. 2002;69(Suppl 2):SII87-SII89.
Last reviewed May 2018 by EBSCO Medical Review Board Michael J. Fucci, DO, FACC Last Updated: 7/10/2018