Supplements labeled “silica hydride” are marketed as a kind of universal cure, said to promote wellness, prevent disease, and potentially cure virtually all illnesses. As a chemical term, “silica hydride” is not well defined, but supplements sold under that name appear to contain a mixture of silicon and oxygen (silica), along with hydrogen (supposedly in the form of hydrides) as well as various minerals. Proponents of this supplement claim that much of human illness results from the presence in ordinary tap water of too many positively charged hydrogen ions. Silica hydride supplements, they say, remedy this by providing negatively charged hydrogen ions (hydride ions). These hydride ions are said to act as powerful antioxidants to increase cellular production of energy and provide many other benefits besides.
From the point of view of standard chemistry, however, the notion of enhancing health through hydride ions is highly problematic. A hydride is a hydrogen ion that carries two extra electrons, making it negatively charged. In its natural state, a hydrogen ion possesses no electrons and, therefore, carries a positive charge. When a hydrogen ion is forced to carry extra electrons, it becomes highly unstable and highly reactive. Hydrides are, in fact, so reactive that as soon as they contact a molecule of water they rip the water molecule to pieces. The result: the hydride disappears, leaving behind hydrogen gas (a substance that, within the body, is relatively inert) and hydroxide ions (the essence of alkalinity, and the active ingredient in Draino). Thus, if “silica hydride” supplements really did provide hydride ions, the ions would instantly disappear the moment they contacted anything moist, such as the mouth, the stomach, or the intestines. During its short existence, the hydride would have no time to act as an antioxidant or perform any other functions. It would simply leave behind a residue of alkalinity, a goal that could be accomplished more easily by, for example, consuming baking soda.
Silica hydride supplements were popularized by the colorful and controversial Patrick Flanagan, an American inventor who was previously responsible for “pyramid power.” In brief, this is the notion (once widely popular in some circles) that it is healthy to sit in or wear pyramidal objects. Flanagan has numerous current interests, one of them being silica hydride. It is his contention that silica hydride supplements enhance health by simulating the especially healthful water naturally consumed by the Hunzas.11
The Hunzas are a real people who live in the tribal areas of Pakistan. They have a long, complex and often tragic history, and at present, they are suspected of harboring Osama bin Laden. In the mythology of the Western healthfood tradition, however, the Hunzas are something else entirely: an emblem of health and longevity.
Based on stories told by a few nonexpert travelers, it became a kind a well-known “fact” that the Hunzas never get cancer and commonly remain spry and healthy long past the age of 100. Whole villages, in fact, were said to be full of people over 140. This cartoonish and ultimately disrespectful caricature of a real people figured prominently in the marketing campaign that made yogurt a common food in America. They were called the “Healthy Hunzas,” and the source of their health was said to be the yogurt that figures prominently in their diet.
More recently, purveyors of silica hydride, Hunza Water, and Hunza Bread claim their products as the source of the Hunza’s healthiness. But, alas, there is no factual relationship between the actual Hunzas and their use as an advertising emblem. The Hunzas are a real people; they get cancer as other people do, and the tales of their amazing longevity were long ago debunked. People who said they were 130 years old on one visit might say they’re 120 on the next visit and 140 when asked the question a year later. This is a phenomenon well-known to anthropologists. In many tribal areas, reported age is a matter of emotion as much as of years; thirty or forty years may be added to a person’s actual age (if, that actual age is even known) to indicate status in the community. Furthermore, bragging about longevity is a normal human trait. The actual life expectancy among the Hunzas appears to be unremarkable.
There is no meaningful evidence to indicate that silica hydride products offer any health benefits.
Websites promoting silica hydride cite a host of supporting studies that supposedly prove the benefits of the product. However, many of these remain unpublished in the archives of the manufacturer 1-3 while others are based on diagnostic techniques that also exist on a far fringe.13 There do exist a number of published and apparently reasonable articles by the inventor of the product and people associated with him,4-9 but, aside from the obvious conflict of interest, their conclusions are merely theoretical in nature, analyzing chemical reactions rather medicinal effects.
Only double-blind, placebo-controlled studies can actually prove a medical treatment effective. A literature search uncovered two such studies of silica hydride supplements published in medical journals. Both of these trials were inspired by the highly questionable claim that silica hydride enhances energy production through effects on ATP, a substance involved in the energy economy of the body. The larger of these studies examined whether a widely marketed silica hydride product could improve sports performance.10 These independent researchers found that silica hydride products did enhance exercise capacity, but so did a placebo, and the two were equally effective. In other words, the supplement did not work. The other study is often reported as positive, but, in fact, measured exercise capacity in too an indirect manner for its results to be meaningful.12
Supplements labeled “silica hydride” are commonly recommended to be taken at a dose of 250 mg twice daily.
No serious adverse effects were reported in the two published human trials noted above.10,12 However, because the term “silica hydride” does not have a precise chemical meaning, it is difficult to make a general statement regarding the safety of substances said to contain it.
1. Osborn G, Salinas H. Texas Institute of Functional Medicines; 1999. Unpublished data.
2. McCord J. University of Colorado Health Sciences Center; 1998. Unpublished data.
3. Raven P, Wasmund W. Fort Worth, TX: University of North Texas Health Science Center; 1999. Unpublished data.
4. Flanagan GP, Purdy-Lloyd K. A silicate mineral supplement, Microhydrin®, traps reduced hydrogen providing in vitro biological antioxidant properties. Proceedings: National Hydrogen Association. 1999;10:595-610.
5. Flanagan GP, Purdy-Lloyd K: A silicate mineral supplement, Microhydrin®, traps reduced hydrogen providing in vitro biological antioxidant properties. Proceedings: National Hydrogen Association 1999;10:595-610.
6. Stephanson CJ, Flanagan GP. Differential metabolic effects on mitochondria by silica hydride using capillary electrophoresis. J Med Food. 2004;7:79-83.
7. Stephanson CJ, Stephanson AM, Flanagan GP. Evaluation of hydroxyl radical-scavenging abilities of silica hydride, an antioxidant compound, by a Fe2+-EDTA-induced 2-hydroxyterephthalate fluorometric analysis. J Med Food. 2003;6:249-53.
8. Stephanson CJ, Flanagan GP. Antioxidant capacity of silica hydride: a combinational photosensitization and fluorescence detection assay. Free Radic Biol Med. 2003;35:1129-1137.
9. Stephanson CJ, Stephanson AM, Flanagan GP. Antioxidant capability and efficacy of Mega-H silica hydride, an antioxidant dietary supplement, by in vitro cellular analysis using photosensitization and fluorescence detection. J Med Food. 2002;5:9-16.
10. Glazier LR, Stellingwerff T, Spriet LL. Effects of microhydrin supplementation on endurance performance and metabolism in well-trained cyclists. Int J Sport Nutr Exerc Metab. 2004;14:560-573.
12. Purdy-Lloyd K, Wasmund W, Smith L, et al. Clinical effects of a dietary antioxidant silicate supplement, microhydrin, on cardiovascular response to exercise. J Med Food. 2001:151-159.
13. Lloyd K, Howard, Clinton. Abstracts of evaluation studies of microhydrin, a functional silicate nanocolloid. Royal Health website. Available at: http://www.royal-health.com/microhydrin-research-abstracts.htm. Accessed 6/25/07
Last reviewed December 2015 by EBSCO CAM Review Board Last Updated: 12/15/2015