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Typhoid Vaccine

What Is Typhoid?

Typhoid (or typhoid fever) is a life-threatening bacterial disease. You get typhoid by:

Typhoid is more common in Asia, Africa, and Latin America, but it does occur in the US. The vaccine doesn’t cover 100% of infections.

Common symptoms involve:

Antibiotics treat typhoid. Without them, symptoms will linger for weeks or months. This can cause further health problems.

What Is the Typhoid Vaccine?

There are 2 types:

Who Should Get Vaccinated and When?

The vaccine is for those who:

What Are the Risks Associated With the Typhoid Vaccine?

Minor reactions from the shot may involve:

Minor reactions from the oral vaccine may involve:

A rare, serious allergic reaction may cause:

Who Should Not Get Vaccinated?

If you are in a high-risk group and need the vaccine, talk to your doctor about the risks.

What Other Ways Can Typhoid Be Prevented Besides Vaccination?

To help lower your chances of typhoid:

What Happens in the Event of an Outbreak?

Health officials will look into the source of an outbreak. This may involve people and places in food service and day care. They will also teach people how to properly wash their hands and prepare food.


Centers for Disease Control and Prevention

Family Doctor—American Academy of Family Physicians


Bhutta ZA, Khan MI, Soofi SB, Ochiai RL. New advances in typhoid fever vaccination strategies. Adv Exp Med Biol. 2011;697:17-39.

Nelson CB, de Quadros C. Coalition against typhoid: a new, global initiative to advance typhoid vaccination. Vaccine. 2011;29(38):6443.

Typhoid vaccine, live. EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T908292/Typhoid-Vaccine-Live. Updated April 18, 2018. Accessed May 15, 2018.

Typhoid VI polysaccharide vaccine. EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T908094/Typhoid-VI-Polysaccharide-Vaccine. Updated April 18, 2018. Accessed May 15, 2018.

Typhoid VIS. Centers for Disease Control and Prevention website. Available at:https://www.cdc.gov/vaccines/hcp/vis/vis-statements/typhoid.html. Updated June 18, 2013. Accessed May 15, 2018.

Last reviewed May 2018 by David L. Horn, MD, FACP  Last Updated: 5/15/2018