Coronary artery disease (CAD) is a the most common type of heart disease. The coronary arteries begin to narrow. This will slow or stop blood flow.
These arteries bring blood to the heart muscle. It supplies the busy heart with oxygen and other nutrients. Slow or stopped blood flow will lead to damage of the heart muscle.
Damage to blood vessel walls causes CAD. Most common factors include:
When plaque hardens it can tear blood vessel walls and cause bleeding. A blood clot will form to help the area heal. However, it can also add to plaque and further shrink path for blood flow.
The risk for CAD is greater in:
Factors that may increase your risk of CAD include:
Other risk factors may include:
CAD itself may not have any signs or symptoms. Often the first sign is a problem with the heart. Weak or blocked blood flow to the heart can cause:
Call for emergency services right away if you think you may be having a heart attack. Early care can stop further harm.
The doctor may suspect CAD based on your family and health past. If you have a high risk of CAD, these tests may be done:
Blood tests to check:
CAD may not be found until after angina appears or a heart attack occurs.
The goals of treatment include:
Options to help reach these goals include:
Medicine can help to manage issues that can make CAD worse. It can also help decrease the risk of complications. Options include:
Early care may decrease damage to the heart. Routine follow up care will be part of the care plan. Other steps that may be recommended include:
Depression, anxiety, and stress can occur with CAD. Talk to your doctor if you need help.
There are also programs to help you make heart healthy changes. It includes help with your food and activity plans.
Surgery may be needed to remove very bad blocks. Options include:
To reduce your risk of CAD:
American Heart Association
National Heart, Lung, and Blood Institute
Heart and Stroke Foundation of Canada
Public Health Agency of Canada
Boden WE, O'Rourke RA, Teo KK, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007;356:1503-1516.
Coronary artery disease–Coronary heart disease. American Heart Association website. Available at:http://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---Coronary-Heart-Disease_UCM_436416_Article.jsp#.WblGd7KGNQI. Updated April 26, 2017. Accessed September 13, 2017.
Coronary artery disease (CAD). EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T116156/Coronary-artery-disease-CAD. Updated June 7, 2017. Accessed September 13, 2017.
Explore coronary artery disease. National Heart, Lung, and Blood Institute website. Available at: https://www.nhlbi.nih.gov/health/health-topics/topics/cad. Updated June 22, 2016. Accessed September 13, 2017.
Management of stable angina. DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T114265/Management-of-stable-angina. Updated April 10, 2017. Accessed September 13, 2017.
4/10/2007 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T114265/Management-of-stable-angina: Boden WE, O'Rourke RA, Teo KK, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007;356(15):1503-1516.
11/7/2007 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T901116/Revascularization-for-coronary-artery-disease-CAD: Bravata DM, Gienger AL, McDonald KM, et al. Systematic Review: The comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery. Ann Intern Med. 2007;147(10):703-716.
1/6/2009 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T113766/Coronary-artery-disease-possible-risk-factors: Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Bingham SA, Khaw KT. Depression and ischemic heart disease mortality: evidence from the EPIC-Norfolk United Kingdom prospective cohort study. Am J Psychiatry. 2008;165(4):515-523.
6/5/2009 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T116156/Coronary-artery-disease-CAD: Sinha R, Cross AJ, Graubard BI, Leitzmann MF, Schatzkin A. Meat intake and mortality: a prospective study of over half a million people. Arch Intern Med. 2009;169(6):562-571.
7/6/2009 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T113884/Physical-activity-for-cardiovascular-disease-prevention: Kodama S, Saito K, Tanaka S, et al. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. JAMA. 2009;301(19):2024-2035.
7/6/2009 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T113766/Coronary-artery-disease-possible-risk-factors: Fung TT, Malik V, Rexrode KM, Manson JE, Willett WC, Hu FB. Sweetened beverage consumption and risk of coronary heart disease in women. Am J Clin Nutr. 2009;89(4):1037-1042.
11/26/2012 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T113766/Coronary-artery-disease-possible-risk-factors: Kivimaki M, Nyberg S, Batty G, et al. Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data. Lancet. 2012;380(9852):1491-1497.
7/21/2014 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T115449/Dietary-considerations-for-cardiovascular-disease-prevention: Afshin A, Micha R, Khatibzadeh S, Mozaffarian D. Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke, and diabetes: a systematic review and meta-analysis. Am J Clin Nutr. 2014;100(1):278-288.
9/29/2016 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T113766/Coronary-artery-disease-possible-risk-factors: Batelaan NM, Seldenrijk A, Bot M, van Balkom AJ, Penninx BW. Anxiety and new onset of cardiovascular disease: critical review and meta-analysis. Br J Psychiatry. 2016;208(3):223-231.
Last reviewed September 2018 by EBSCO Medical Review Board Michael J. Fucci, DO, FACC Last Updated: 7/31/2018