Rutgers Cancer Institute of New Jersey
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Gangrene is the death of body tissue from lack of blood. There are two types:
It is caused by a lack of blood to tissues in the body.
Things that raise the risk are:
Symptoms start slow and then get worse. They may be:
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The doctor will ask about your symptoms and health history. A physical exam will be done.
Blood tests will be done to check for infection. Discharge and tissue may also be tested.
Images may be taken. This can be done with:
Some people may need surgery to confirm the diagnosis.
Treatment depends on how much tissue has died and whether it has spread.
Medicine may be given to treat infection and ease pain.
Some people may need surgery to:
Some people may be helped by hyperbaric oxygen therapy. This is breathing 100% oxygen in a sealed chamber. It may improve blood flow and oxygen levels in the body.
To lower the chance of gangrene:
American Diabetes Association
Family Doctor—American Academy of Family Physicians
Clostridial myonecrosis. EBSCO DynaMed website. Available at:https://www.dynamed.com/condition/clostridial-myonecrosis. Updated October 27, 2017. Accessed October 31, 2019.
Gangrene. Johns Hopkins Medicine website. Available at: http://www.hopkinsmedicine.org/healthlibrary/conditions/infectious_diseases/gangrene_134,151. Accessed October 31, 2019.
Gangrene. NHS Choices website. Available at: http://www.nhs.uk/Conditions/Gangrene/Pages/Introduction.aspx. Updated August 16, 2018. Accessed October 31, 2019.
Sepsis in adults. EBSCO DynaMed website. Available at:https://www.dynamed.com/condition/sepsis-in-adults. Updated October 4, 2018. Accessed October 31, 2019.
Stevens DL, Bisno AL, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.
Last reviewed September 2019 by EBSCO Medical Review Board Daniel A. Ostrovsky, MD Last Updated: 10/31/2019