Rutgers Cancer Institute of New Jersey
195 Little Albany Street
New Brunswick, NJ 08903-2681
Polymyositis is a rare disease of the muscles. It makes muscles inflamed or swollen. It can lead to severe movement problems. Treatment can help.
Copyright © Nucleus Medical Media, Inc.
Changes in genes may be the cause. The altered genes change how your immune system responds to the environment. It leads to attack of muscles by the immune system.
Polymyositis is more common in:
Your risk is higher if people in your family have lupus.
The muscles near the trunk of the body are affected more often. You may have:
Polymyositis can also lead to:
You will be asked about your symptoms and health history. A physical exam will be done.
The following tests may be done to confirm muscle disease:
The disease starts slowly and gets worse over time. There is no cure. The muscles will get weaker and more painful without treatment.
Medical care can help with your strength and movement. Some treatment options include:
Medicine will depend on your specific needs. Options include:
Weakness of muscles can cause a loss of function. Therapy may help you work around these changes. Options include:
There are no ways to prevent polymyositis.
American Autoimmune Related Diseases Association
The Myositis Association
Diagnosis. The Myositis Association website. Available at: http://www.myositis.org/learn-about-myositis/diagnosis. Updated March 2015. Accessed May 11, 2016.
Gordon PA, Winer JB, Hoogendijk JE, Choy EH. Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis. Cochrane Database Syst Rev. 2012;8:CD003643.
Idiopathic inflammatory myopathy. EBSCO DynaMed Plus website. Available at:http://www.dynamed.com/topics/dmp~AN~T115684/Idiopathic-inflammatory-myopathy. Updated November 20, 2017. Accessed June 13, 2018.
Myositis. Ortho Info—American Academy of Orthopaedic Surgeons website. Available at: http://orthoinfo.aaos.org/topic.cfm?topic=A00198. Updated June 2017. Accessed June 13, 2018.
NINDS polymyositis information page. National Institute of Neurological Disorders and Stroke website. Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Polymyositis-Information-Page. Accessed June 13, 2018.
Treatment and disease management. Myositis Association website. Available at: http://www.myositis.org/learn-about-myositis/treatment. Accessed June 13, 2018.
Types of myositis. Myositis Association website. Available at: http://www.myositis.org/learn-about-myositis/types-of-myositis. Accessed June 13, 2018.
11/9/2015 DynaMed Plus Systematic Literature Surveillancehttp://www.dynamed.com/topics/dmp~AN~T115684/Idiopathic-inflammatory-myopathy: Kuo CF, Grainge MJ, Valdes AM, et al. Familial aggregation of systemic lupus erythematosus and coaggregation of autoimmune diseases in affected families. JAMA Intern Med. 2015;175(9):1518-1526.
Last reviewed May 2018 by EBSCO Medical Review Board Rimas Lukas, MD Last Updated: 6/12/2018